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Table 3 Top 20 ASD-associated differentially expressed genes by log2(fold change) in meta-analysis

From: A meta-analysis of two high-risk prospective cohort studies reveals autism-specific transcriptional changes to chromatin, autoimmune, and environmental response genes in umbilical cord blood

Probe ID Gene symbol MARBLES EARLI Meta-analysis
log2(FC) p value log2(FC) p value log2(FC) SE p value q value
17004333 TUBB2A 0.36 9.6E−03 0.33 2.1E−01 0.35 0.12 4.8E−03 0.75
17094496 MIR1299 0.28 6.1E−03 0.15 2.3E−01 0.23 0.08 4.3E−03 0.75
17065047 LOC389831 0.26 6.1E−03 0.16 2.4E−01 0.23 0.08 4.2E−03 0.74
17063807 TRBV11-2 0.22 1.7E−02 0.19 1.7E−01 0.21 0.08 7.0E−03 0.79
16812322 RNU6-667P 0.13 1.4E−01 0.34 4.1E−03 0.20 0.07 3.7E−03 0.73
16662296 RNA5SP42 0.22 3.1E−03 0.12 4.4E−01 0.20 0.07 3.0E−03 0.73
17079513 RNU6-748P 0.15 1.3E−01 0.26 1.5E−02 0.20 0.07 6.4E−03 0.78
16837063 SNORA76C 0.20 2.5E−02 0.19 1.5E−01 0.20 0.08 9.2E−03 0.83
16755265 MIR331 0.15 2.1E−02 0.26 7.0E−04 0.20 0.05 6.4E−05 0.47
16698226 LINC01136 0.17 3.0E−02 0.30 4.9E−02 0.20 0.07 5.4E−03 0.76
16738477 RP11-872D17.8 0.22 2.6E−03 0.12 3.2E−01 0.19 0.06 2.3E−03 0.72
16797869 HERC2P7 − 0.17 4.7E−02 − 0.22 5.4E−02 − 0.19 0.07 7.0E−03 0.79
16778413 TPTE2P5 − 0.25 4.9E−04 − 0.01 9.2E−01 − 0.19 0.06 2.3E−03 0.72
16865104 MIR519A2 − 0.28 3.5E−05 − 0.07 3.3E−01 − 0.19 0.05 1.8E−04 0.70
17113511 RNU6-154P − 0.22 1.9E−03 − 0.13 2.6E−01 − 0.20 0.06 1.4E−03 0.72
16810171 RP11-507B12.1 − 0.23 3.1E−03 − 0.16 1.8E−01 − 0.21 0.07 1.6E−03 0.72
17062251 RNA5SP241 − 0.15 5.8E−02 − 0.45 3.4E−03 − 0.21 0.07 2.6E−03 0.72
16788697 SNORD114-28 − 0.29 9.1E−03 − 0.17 2.8E−01 − 0.25 0.09 6.7E−03 0.78
16928422 CTA-390C10.10 − 0.17 9.8E−02 − 0.55 4.3E−04 − 0.29 0.09 7.2E−04 0.72
16733787 RP11-304M2.6 − 0.28 1.5E−02 − 0.40 5.3E−02 − 0.31 0.10 2.6E−03 0.72
  1. ASD autism spectrum disorder, FC fold change, SE standard error