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Fig. 7 | Molecular Autism

Fig. 7

From: A meta-analysis of two high-risk prospective cohort studies reveals autism-specific transcriptional changes to chromatin, autoimmune, and environmental response genes in umbilical cord blood

Fig. 7

Cell type proportions are correlated with demographic factors in meta-analysis. a Barplot of mean estimated proportion of each cell type by diagnosis and study from CIBERSORT using default adult peripheral blood reference panel. b Heatmap of meta-analysis biweight midcorrelation Z-scores of cell type proportions with sample covariates (MARBLES: ASD n = 41, Non-TD n = 44, TD n = 76; EARLI: ASD n = 19, Non-TD n = 47, TD n = 43). Z-scores from the individual studies were combined using Stouffer’s method with weights given by the square root of sample n. p values were adjusted using the FDR method (*q < 0.05)

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Molecular Autism

ISSN: 2040-2392