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Table 1 Discordant group differentially expressed genes at FDR < 20%. For each gene, the estimated fold change, average expression (in log counts per million), p value and FDR adjusted p values from edgeR are given. The final column indicates if the gene showed a consistent direction of differential expression across all twin pairs and the arrow which direction this was in (increased or decreased expression in ASC affected compared to unaffected co-twin)

From: RNA sequencing of identical twins discordant for autism reveals blood-based signatures implicating immune and transcriptional dysregulation

ensembl gene idhgnc symbolchrlogFClogCPMP valueFDRcons. dir
ENSG00000211892IGHG4142.14831.94842.11E-083.76E-04 
ENSG00000126860EVI2A17− 0.65815.12082.88E-061.94E-02
ENSG00000207445SNORD15B11− 0.85243.06383.28E-061.94E-02
ENSG00000150681RGS181− 0.52526.98772.49E-051.11E-01
ENSG00000139679LPAR613− 0.60904.79903.46E-051.23E-01
ENSG00000163682RPL94− 0.66456.83915.01E-051.48E-01 
ENSG00000163736PPBP4− 0.48307.42916.32E-051.60E-01
ENSG00000035499DEPDC1B5− 1.31130.54931.00E-041.86E-01
ENSG00000187534PRR13P5191.52200.49471.14E-041.86E-01 
ENSG00000198339HIST1H4I6− 0.66943.74981.15E-041.86E-01
ENSG00000156482RPL308− 0.50208.36151.18E-041.86E-01
ENSG00000229117RPL4112− 0.56826.92331.28E-041.86E-01
ENSG00000166710B2M15− 0.565511.31251.44E-041.86E-01
ENSG00000138180CEP5510− 1.43660.24291.48E-041.86E-01 
ENSG00000184825HIST1H2AH6− 0.74103.62271.61E-041.86E-01 
ENSG00000145425RPS3A4− 0.74366.88231.67E-041.86E-01