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Table 1 Discordant group differentially expressed genes at FDR < 20%. For each gene, the estimated fold change, average expression (in log counts per million), p value and FDR adjusted p values from edgeR are given. The final column indicates if the gene showed a consistent direction of differential expression across all twin pairs and the arrow which direction this was in (increased or decreased expression in ASC affected compared to unaffected co-twin)

From: RNA sequencing of identical twins discordant for autism reveals blood-based signatures implicating immune and transcriptional dysregulation

ensembl gene id hgnc symbol chr logFC logCPM P value FDR cons. dir
ENSG00000211892 IGHG4 14 2.1483 1.9484 2.11E-08 3.76E-04  
ENSG00000126860 EVI2A 17 − 0.6581 5.1208 2.88E-06 1.94E-02
ENSG00000207445 SNORD15B 11 − 0.8524 3.0638 3.28E-06 1.94E-02
ENSG00000150681 RGS18 1 − 0.5252 6.9877 2.49E-05 1.11E-01
ENSG00000139679 LPAR6 13 − 0.6090 4.7990 3.46E-05 1.23E-01
ENSG00000163682 RPL9 4 − 0.6645 6.8391 5.01E-05 1.48E-01  
ENSG00000163736 PPBP 4 − 0.4830 7.4291 6.32E-05 1.60E-01
ENSG00000035499 DEPDC1B 5 − 1.3113 0.5493 1.00E-04 1.86E-01
ENSG00000187534 PRR13P5 19 1.5220 0.4947 1.14E-04 1.86E-01  
ENSG00000198339 HIST1H4I 6 − 0.6694 3.7498 1.15E-04 1.86E-01
ENSG00000156482 RPL30 8 − 0.5020 8.3615 1.18E-04 1.86E-01
ENSG00000229117 RPL41 12 − 0.5682 6.9233 1.28E-04 1.86E-01
ENSG00000166710 B2M 15 − 0.5655 11.3125 1.44E-04 1.86E-01
ENSG00000138180 CEP55 10 − 1.4366 0.2429 1.48E-04 1.86E-01  
ENSG00000184825 HIST1H2AH 6 − 0.7410 3.6227 1.61E-04 1.86E-01  
ENSG00000145425 RPS3A 4 − 0.7436 6.8823 1.67E-04 1.86E-01