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Table 3 SRS sub-scale score comparison stratified by genotype, ASD status, and sex

From: Neuropsychiatric phenotypes and a distinct constellation of ASD features in 3q29 deletion syndrome: results from the 3q29 registry

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Mean ± SD p value Mean ± SD p value Mean ± SD p value Mean ± SD p value Mean ± SD p value Mean ± SD p value
Genotype
Control 47.04 ± 8.88 45.27 ± 7.64 45.88 ± 8.14 46.13 ± 7.66 47.66 ± 8.51 45.50 ± 7.74
3q29Del 67.33 ± 13.28 1.45E− 13 69.06 ± 15.51 1.20E− 15 69.69 ± 13.92 < 2.00E− 16 62.10 ± 13.52 1.62E− 10 77.31 ± 14.25 < 2.00E− 16 69.52 ± 14.63 < 2.00E− 16
Sex
Male control 45.97 ± 9.15 45.23 ± 7.42 45.73 ± 6.34 46.57 ± 6.58 47.63 ± 5.59 45.37 ± 6.60
Male 3q29Del 69.92 ± 13.92 7.61E− 09 71.08 ± 17.65 1.07E− 08 72.12 ± 15.47 1.74E− 10 63.92 ± 15.23 3.39E− 06 79.92 ± 14.82 2.84E− 13 72.00 ± 16.34 7.12E− 10
Female control 48.27 ± 8.56 45.31 ± 8.03 46.04 ± 9.95 45.62 ± 8.85 47.69 ± 11.08 45.65 ± 9.01
Female 3q29Del 64.27 ± 12.08 4.52E− 06 66.68 ± 12.51 1.29E− 08 66.82 ± 11.52 2.99E− 08 59.95 ± 11.14 1.36E− 05 74.23 ± 13.22 1.30E− 09 66.59 ± 12.02 1.87E− 08
ASD Status
Control 47.04 ± 8.88 45.27 ± 7.64 45.88 ± 8.14 46.13 ± 7.66 47.66 ± 8.51 45.50 ± 7.74
No ASD diagnosis 3q29Del 62.61 ± 13.20 5.17E− 09 64.10 ± 15.80 5.77E− 11 64.61 ± 13.54 1.20E− 12 58.00 ± 13.15 1.42E− 06 70.58 ± 11.50 < 2.00E− 16 64.13 ± 14.39 5.19E− 12
ASD diagnosis 3q29Del 75.94 ± 8.33 2.43E− 15 78.12 ± 10.18 < 2.00E− 16 78.94 ± 9.18 < 2.00E− 16 69.59 ± 10.99 5.12E− 12 89.59 ± 10.04 < 2.00E− 16 79.35 ± 9.02 < 2.00E− 16
  1. Comparison of mean scores on the SRS sub-scales between study participants with 3q29Del and controls. 3q29Del participants were stratified by ASD status and sex for further analysis. p values were calculated using simple linear regression, adjusting for age, race, and sex