Table 1 Dup15q syndrome reference cohort. Cognitive ability is reported as developmental quotient derived (DQ) from age-appropriate developmental scales. Calculations of mean and standard deviation (SD) for DQ scores ignore missing data reported in rows ‘missing DQ’ row

Dup15q reference cohort

13

14

27

Dup15q age (months, mean ± SD)

80.0 ± 42.7 (min = 9, max = 175)

56.9 ± 37.0 (min = 18, max = 156)

68.0 ± 40.8 (min = 9, max = 175)

Dup15q DQ (mean ± SD)

45.2 ± 23.7

35.8 ± 16.8

40.5 ± 20.6

Dup15q missing DQ

1

2

3

Dup15q ADOS calibrated severity score

6.13 ± 2.59

7.33 ± 1.44

6.85 ± 2.01

Dup15q missing ADOS

5

2

7

TD sample

N/A

N/A

14

TD age (months, mean ± SD)

N/A

N/A

55.0 ± 28.5 (min = 16, max = 111)

TD DQ (mean ± SD)

N/A

N/A

118 ± 15.5