Fig. 2

Behavioral phenotype of adolescent (P29) VPA male mice. a–c In the open field test, VPA mice (n = 9; black bars) show similar total locomotor activity and higher anxiety-like behaviors than CTR (n = 13; white bars); d–f in the social interaction test, VPA mice (n = 11; black bars) show reduced interest to approach and to investigate (sniffing events) the novel animal than CTR mice (n = 14; white bars). Mean ± SEM, *p < 0.05, and ***p < 0.001. In Additional file 1, see Figure S2 for area delimitation and representative videos for the open field (Videos S1 and S2) and social interaction test (Videos S3 and S4)