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Table 1 Descriptive statistics

From: Latent trajectories of adaptive behaviour in infants at high and low familial risk for autism spectrum disorder

 

Tot

C1 decreasing adaptive behaviour

C2 average/stable adaptive behaviour

C3 recovering adaptive behaviour

 

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Age

 8 m

8.1

1.2

7.9

1.5

7.9

1.1

8.7

1.3

 14 m

14.4

1.3

14.1

1.4

14.3

1.2

15.1

1.4

 24 m

25.0

1.8

25.7

2.7

25.0

1.8

25.0

1.5

 36 m

38.8

2.9

40.2

3.6

38.6

3.0

38.9

2.2

VABS

 Comm 8 m

96.1

15.9

108.2

14.7

99.2

12.6

77.0

14.2

 Comm 14 m

96.7

13.3

91.1

15.9

98.0

13.1

93.4

11.8

 Comm 24 m

103.7

13.0

88.7

20.1

104.7

11.3

106.6

11.2

 Comm 36 m

101.1

14.1

86.8

19.8

102.2

12.9

102.9

12.6

 DL 8 m

100.1

13.7

106.7

18.4

101.3

12.3

91.9

13.8

 DL 14 m

95.2

13.1

90.6

17.8

96.5

13.0

91.7

10.0

 DL 24 m

105.7

12.9

94.4

20.0

106.7

11.9

106.7

10.1

 DL 36 m

103.2

13.0

87.9

20.9

104.1

11.5

106.2

9.3

 Mot 8 m

89.8

16.3

98.4

24.2

91.8

14.5

76.9

12.7

 Mot 14 m

100.3

12.8

99.1

14.9

101.9

12.5

94.3

11.4

 Mot 24 m

100.1

10.9

90.2

12.0

101.2

10.4

100.4

10.1

 Mot 36 m

93.8

12.4

84.6

14.7

94.7

11.9

94.1

11.7

 Soc 8 m

100.1

12.8

109.6

19.7

101.4

10.6

90.0

11.7

 Soc 14 m

97.7

11.7

97.5

13.8

98.7

11.8

93.6

9.7

 Soc 24 m

101.0

11.6

89.1

18.0

101.5

10.6

104.1

8.7

 Soc 36 m

97.8

12.9

85.6

17.9

98.3

12.1

101.2

10.5

MSEL

 ELC 8 m

104.2

15.0

106.2

18.2

104.9

14.7

100.4

14.6

 ELC 14 m

98.5

16.0

86.2

19.3

100.6

15.7

95.6

12.6

 ELC 24 m

104.7

19.9

81.9

25.8

106.8

18.0

105.7

19.1

 ELC 36 m

107.7

22.7

89.6

26.7

108.6

22.7

111.9

17.4

ADOS at 36 m1

 CSS-Tot

2.95

2.40

3.84

3.00

2.94

2.43

2.60

1.90

 CSS-SA

3.40

2.51

4.00

2.89

3.43

2.55

3.02

2.14

 CSS-RRB

4.29

2.61

5.42

2.73

4.14

2.58

4.42

2.62

ADI-R at 36 m2

 ADI-Comm3

3.25

4.17

7.00

5.75

2.96

3.85

2.67

3.81

 ADI-Soc3

3.08

4.31

7.55

7.76

2.66

3.68

2.67

3.35

 ADI-RBI4

1.15

1.98

2.40

2.58

1.12

1.93

0.70

1.63

SCQ at 36 m2

 SCQ-Tot3

5.32

6.11

11.1

8.83

5.02

5.64

3.91

5.03

Clinical outcome at 36 m5

n (%)

n (%)

n6 (%)

n (%)

 LR

74 (31)

4 (20)

56 (32)

14 (32)

 HR-Typ

87 (36)

6 (30)

63 (36)

18 (42)

 HR-Atyp

44 (18)

2 (10)

34 (19)

8 (19)

 HR-ASD

34 (14)

8 (40)

23 (13)

3 (7)

Gender

 Female

122 (51)

7 (35)

92 (52)

23 (53)

 Male

118 (49)

13 (65)

85 (48)

20 (47)

  1. This table shows the descriptive statistics for the entire sample and for the different trajectory classes of adaptive behaviour
  2. Tot entire sample, C1–C3 classes in trajectories of adaptive behaviour7, VABS Vineland Adaptive Behavior Scales, Comm communication score, DL daily living score, Mot motor score, Soc socialisation score, MSEL Mullen Scales of Early Learning, ELC early learning composite score, ADOS Autism Diagnostic Observation Schedule, CSS Calibrated Severity Score, ADI-R Autism Diagnostic Interview-Revised, ADI-Comm Communication domain score (ADI-R), ADI-Soc Social domain score (ADI-R), ADI-RBI Restricted Behaviors and Interests domain score (ADI-R), SCQ Social Communication Questionnaire, SCQ-Tot total score (SCQ), LR low-risk controls, HR high-risk siblings, HR-Typ typically developing siblings, HR-Atyp atypically developing siblings (no ASD), HR-ASD siblings with ASD
  3. 1Data were available for a subsample of n = 235 infants
  4. 2Data were available for a subsample of n = 239 infants
  5. 3Significant difference per class with p < 0.001
  6. 4Significant difference per class with p < 0.05
  7. 5Clinical outcome vs class membership: χ2 [6] = 13.39, p = 0.037
  8. 6One infant in this class did not receive a clinical outcome evaluation at 36 months
  9. 7C1, decreasing adaptive behaviour; C2, average/stable adaptive behaviour; C3, recovering adaptive behaviour
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Molecular Autism

ISSN: 2040-2392