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Fig. 3 | Molecular Autism

Fig. 3

From: Transcriptomic metaanalyses of autistic brains reveals shared gene expression and biological pathway abnormalities with cancer

Fig. 3

Top 10 ASD- and cancer-associated pathways extracted from 3 different molecular signature databases (Hallmarks, KEGG and Reactome). Yellow and purple segments indicate pathways downregulated and upregulated in cancer, respectively, whereas red and green segments denote pathways downregulated and upregulated in ASD, respectively. The length of the yellow and purple bars indicates the number of studied cancers that represent the reported direction of deregulation for this particular pathway. a Pathways jointly upregulated in ASD and cancer. b Pathways upregulated in ASD and downregulated in cancer. c Pathways jointly downregulated in ASD and cancer. d Pathways downregulated in ASD and upregulated in cancer

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