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Fig. 3 | Molecular Autism

Fig. 3

From: The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice

Fig. 3

Nrxn2α KO mice have increased fractional anisotropy (FA) and axial (AD) and radial diffusivity (RD) in the orbitofrontal cortex (OFC) and the anterior cingulate cortex (ACC). FA was significantly different between wild-type and Nrxn2α KO mice for FA in the OFC (a) and ACC (e), but ADC was not significantly changed in Nrxn2α KO mice in both prefrontal regions (b and f). The OFC has significantly increased AD and RD (c and d), whereas only AD was increased in the ACC (gh). **p < 0.01, *p < 0.05. Error bars represent s.e.m. Wild type n = 6, Nrxn2α KO n = 6

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