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Fig. 2 | Molecular Autism

Fig. 2

From: The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice

Fig. 2

Deletion of Nrxn2α increases amygdala fractional anisotropy (FA) but not apparent diffusion coefficient (ADC). DTI images of the amygdala was segmented at two regions; the whole amygdala in the anterior to posterior extent or the basolateral amygdala (BLA) centred at bregma − 1.94 mm. FA of the whole amygdala structure was significantly increased (a) but was decreased in the BLA (b). However, ADC was similar between the genotypes (c and d). Axial (AD) (e) and radial diffusivity (RD) (f) was unaltered in the amygdala. **p < 0.01, *p < 0.05. Error bars represent s.e.m. Wild type n = 6, Nrxn2α KO n = 6

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