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Fig. 8 | Molecular Autism

Fig. 8

From: Haploinsufficiency of autism causative gene Tbr1 impairs olfactory discrimination and neuronal activation of the olfactory system in mice

Fig. 8

Rescue effect of D-cycloserine on olfactory discrimination in Tbr1+/− mice. ab Thirty minutes after D-cycloserine (DCS) treatment, mice were subjected to the sensation-habituation-dishabituation test, as indicated in the lower panel of Fig. 1a. a Time spent sniffing limonene in the first trial and b olfactory habituation are comparable between WT and Tbr1+/− mice. cd D-cycloserine improves olfactory discrimination of Tbr1+/− mice in trial 6. Data represent mean plus SEM and the results of individual mice are shown. *p < 0.05; **p < 0.01; ***p < 0.001

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