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Fig. 7 | Molecular Autism

Fig. 7

From: Haploinsufficiency of autism causative gene Tbr1 impairs olfactory discrimination and neuronal activation of the olfactory system in mice

Fig. 7

Impaired neuronal activation in the piriform and perirhinal cortices due to Tbr1 haploinsufficiency. ac Two hours after exposure to limonene (L) or mineral oil (M), mouse brains were harvested for C-FOS staining. Insets are DAPI images to outline the structure of different brain regions (the piriform (PC) and perirhinal (PrC) cortices and the olfactory tubercle (OT)). de. Quantitative data showing the numbers of C-FOS-positive cells in WT (d) and Tbr1+/− mice (e). Data represent mean plus SEM and the results of individual mice are shown. **p < 0.01, ***p < 0.001. Scale bars 200 μm (a); 100 μm (b); 100 μm (c)

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