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Fig. 6 | Molecular Autism

Fig. 6

From: Haploinsufficiency of autism causative gene Tbr1 impairs olfactory discrimination and neuronal activation of the olfactory system in mice

Fig. 6

Increased neuronal activation in the glomerular layer of WT littermates but not Tbr1+/− mice. a-d Two hours after exposure to limonene or mineral oil, Tbr1+/− mice and WT littermates were subjected to C-FOS staining to monitor neuronal activation. a’–d’ High magnification images of insets in (a)–(d). ef Quantification of C-FOS-positive cell number in the glomerular layer (GL), external plexiform layer (EPL), and mitral cell layer (MCL). Data represent mean plus SEM and the results of individual mice are shown. * p < 0.05. Scale bars 200 μm (original images); 100 μm (enlarged images)

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