|
Interpreted biomarker component
|
Biomarker name
|
Factor loadinga
|
Explained variance (%)
|
Explained variance cumulative (%)
|
|---|
|
PC-1
|
PFOS
|
0.853
|
12.27
|
12.27
|
|
PFOA
|
0.696
| | |
|
PFOSA
|
0.523
| | |
|
Cu
|
0.452
| |
|
AR-AEQ
|
− 0.386
| |
|
ER-EEQ
|
0.363
| |
|
Fe
|
0.358
| |
|
PC-2
|
AhR-TEQ
|
0.834
|
10.08
|
22.35
|
|
Fe
|
0.758
| |
|
AR-AEQ
|
0.658
| |
|
PC-3
|
I
|
0.763
|
10.05
|
32.40
|
|
Zn
|
0.706
| | |
|
T3-ThEQ
|
0.589
| | |
|
Cr
|
0.427
| | |
|
Pb
|
0.326
| | |
|
PC-4
|
Mn
|
0.777
|
8.43
|
40.83
|
|
E2
|
0.763
| | |
|
ER-EEQ
|
0.347
| | |
|
Cr
|
0.316
| | |
|
PC-5
|
Pb
|
0.778
|
8.34
|
49.17
|
|
Cd
|
0.729
| | |
|
Cu
|
0.424
| | |
|
Cr
|
0.327
| | |
|
PC-6
|
Se
|
0.746
|
7.76
|
56.93
|
|
As
|
0.691
| | |
|
Cu
|
0.480
| | |
|
PC-7
|
testosterone
|
0.818
|
7.71
|
64.63
|
|
ER-EEQ
|
0.622
| | |
- PC principal component
- aFactor loadings are the correlation coefficients between the original variables (levels of chemicals and receptor transactivities) and the extracted components. Variable levels are sorted by the size of the loading coefficients. Variable levels with factor loading below |0.30| are not listed
