Skip to main content

Table 9 Rotated factor loading of components identified by principal component analysis (PCA)

From: Autism spectrum disorders, endocrine disrupting compounds, and heavy metals in amniotic fluid: a case-control study

Interpreted biomarker component

Biomarker name

Factor loadinga

Explained variance (%)

Explained variance cumulative (%)

PC-1

PFOS

0.853

12.27

12.27

PFOA

0.696

  

PFOSA

0.523

  

Cu

0.452

 

AR-AEQ

− 0.386

 

ER-EEQ

0.363

 

Fe

0.358

 

PC-2

AhR-TEQ

0.834

10.08

22.35

Fe

0.758

 

AR-AEQ

0.658

 

PC-3

I

0.763

10.05

32.40

Zn

0.706

  

T3-ThEQ

0.589

  

Cr

0.427

  

Pb

0.326

  

PC-4

Mn

0.777

8.43

40.83

E2

0.763

  

ER-EEQ

0.347

  

Cr

0.316

  

PC-5

Pb

0.778

8.34

49.17

Cd

0.729

  

Cu

0.424

  

Cr

0.327

  

PC-6

Se

0.746

7.76

56.93

As

0.691

  

Cu

0.480

  

PC-7

testosterone

0.818

7.71

64.63

ER-EEQ

0.622

  
  1. PC principal component
  2. aFactor loadings are the correlation coefficients between the original variables (levels of chemicals and receptor transactivities) and the extracted components. Variable levels are sorted by the size of the loading coefficients. Variable levels with factor loading below |0.30| are not listed
Back to article page

Molecular Autism

ISSN: 2040-2392