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Table 9 Rotated factor loading of components identified by principal component analysis (PCA)

From: Autism spectrum disorders, endocrine disrupting compounds, and heavy metals in amniotic fluid: a case-control study

Interpreted biomarker component Biomarker name Factor loadinga Explained variance (%) Explained variance cumulative (%)
PC-1 PFOS 0.853 12.27 12.27
PFOA 0.696   
PFOSA 0.523   
Cu 0.452  
AR-AEQ − 0.386  
ER-EEQ 0.363  
Fe 0.358  
PC-2 AhR-TEQ 0.834 10.08 22.35
Fe 0.758  
AR-AEQ 0.658  
PC-3 I 0.763 10.05 32.40
Zn 0.706   
T3-ThEQ 0.589   
Cr 0.427   
Pb 0.326   
PC-4 Mn 0.777 8.43 40.83
E2 0.763   
ER-EEQ 0.347   
Cr 0.316   
PC-5 Pb 0.778 8.34 49.17
Cd 0.729   
Cu 0.424   
Cr 0.327   
PC-6 Se 0.746 7.76 56.93
As 0.691   
Cu 0.480   
PC-7 testosterone 0.818 7.71 64.63
ER-EEQ 0.622   
  1. PC principal component
  2. aFactor loadings are the correlation coefficients between the original variables (levels of chemicals and receptor transactivities) and the extracted components. Variable levels are sorted by the size of the loading coefficients. Variable levels with factor loading below |0.30| are not listed