Autism spectrum disorders, endocrine disrupting compounds, and heavy metals in amniotic fluid: a case-control study

Table 4 Levels of hormones and receptor transactivities in amniotic fluid

E2 17β-estradiol, ER-EEQ the combined effect on ER of endogenous estrogen and xeno-estrogens (EDCs) given as estradiol equivalent, EDCs-EEQ the integrated estrogenic effect induced only by xeno-estrogens (EDCs) alone given as estradiol equivalent, DHT dihydrotestosterone, AR-AEQ the combined effect on AR of endogenous androgens and xeno-androgens (EDCs) given as androgen equivalent, EDC-AEQ the integrated androgenic effect induced only by xeno-androgens (EDCs) alone given as androgen equivalent, T3 L-3,5,3′-triiiodothyronine, T3-ThEQ the combined proliferation effect (PE) of endogenous thyroid and xeno-thyroid hormone-like compounds (EDCs) given as thyroid equivalent, AhR-TEQ the combined effect on AhR of dioxin-like compounds given as TCDD equivalent, FDR (q_value) false discovery rate. See the “Methods” section and Table 1 for the different calculations. The difference between cases and controls was compared using non-parametric Mann-Whitney test

ISSN: 2040-2392