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Table 10 Odds ratio and 95% confidence intervals for ASD according to PCA components

From: Autism spectrum disorders, endocrine disrupting compounds, and heavy metals in amniotic fluid: a case-control study

  Crude   Adjusteda   
n (cases/controls) OR (95% CI) p n (cases/controls) OR (95% CI) p FDR (qvalues)
PC-1 29/44 0.236 (0.092, 0.607) 0.003 29/44 0.100 (0.016, 0.630) 0.014 0.098
PC-2 29/44 0.793 (0.449, 1.398) 0.422 29/44 0.943 (0.456, 1.948) 0.873 0.961
PC-3 29/44 1.180 (0.733, 1.897) 0.496 29/44 1.059 (0.538, 2.082) 0.868 0.868
PC-4 29/44 1.167 (0.724, 1.880) 0.526 29/44 1.027 (0.363, 2.903) 0.961 0.961
PC-5 29/44 1.064 (0.668, 1.695) 0.793 29/44 1.431 (0.810, 2.531) 0.218 0.763
PC-6 29/44 1.061 (0.664, 1.697) 0.804 29/44 1.258 (0.661, 2.393) 0.485 0.849
PC-7 29/44 1.25 (0.773, 2.025) 0.363 29/44 1.354 (0.662, 2.767) 0.407 0.849
  1. PC principal component, FDR (qvalue) false discovery rate. For component of PC-1~PC-7, see Table 9. Italicized values indicate statistically significant (p < 0.05 and FDR qvalue < 0.25)
  2. aAdjusted for children’s birth year, children’s sex, mother age at delivery, father age at child birth, birth weight, gestational week at sampling, gestational age at birth, Apgar score, parity, and congenital malformation