Fig. 4
From: Brain hyperserotonemia causes autism-relevant social deficits in mice
Gene expression changes in the brain in Sert HZ and KO mice that received a normal diet. Whole-genome gene expression profiles in whole brains were compared between Sert HZ and KO mice. a Scatter plot showing the relationship of gene expression changes in Sert HZ (HZ[Ctrl]) and KO (KO[Ctrl]) mice compared with WT (WT[Ctrl]) mice. b Number of genes with significant changes in levels of expression, showing the correlation of 37 genes whose expression levels were changed in both HZ(Ctrl) and KO(Ctrl) mice. c Expression levels in the three groups of genes in Fig. 3b relative to WT(Ctrl). d Top 10 drugs with gene expression profiles that were similar to the 37 genes in Fig. 3b. Bold, drugs related to 5-HT signaling