Fig. 1

Expression of ASD-relevant social deficits in Sert HZ and KO mice. a Active interaction time over 10 min in the social interaction test. The data are expressed as mean ± SEM. *P < 0.05, **P < 0.01, two-way ANOVA followed by Fisher’s PLSD test. b, c Active social interaction time for 10 min in the social approach phase in the three-chamber test. d, e Active social interaction time over 10 min in the social preference phase in the three-chamber test. The data are expressed as mean ± SEM. *P < 0.05, **P < 0.01, paired Student’s t test (b–e)