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Table 2 Adverse events

From: A pilot dose finding study of pioglitazone in autistic children

Event # Participants
Eye disorders
 Eye redness 1
Oral/gastrointestinal disorders
 Vomiting 3
 Abdominal pain 2
 Constipation 1
 Diarrhea 1
 Mouth sore/dry lips 2
 Tooth problem 6
General disorders
 Increased energy/behavioral activation 3
 Fatigue 1
 Increased sweating 1
Immune system disorders  
 Neutropenia 3
Infections
 Fever 1
 Gastroenteritis 3
 Upper respiratory tract infection 11
Injury
 Skin bruise 1
 Skin burn 1
 Insect bite 2
Appetite
 Decreased appetite 2
 Increased appetite 1
Musculoskeletal
 Muscle pain/cramps 2
Nervous system disorder
 Concentration difficulty 1
 Headache 1
Psychiatric disorders
 Disinhibition/silliness 2
 Increased impulsivity 1
 Emotional lability 2
 Increased aggression/irritation/anger 5
 Insomnia (initial/mid-cycle) 6
 Negative thoughts 1
 Self-injurious behavior 2
Genitourinary
 Diurnal/nocturnal enuresis 3
 Increased urinary frequency 1
 Genital discomfort 1
Respiratory
 Cough 1
 Nasal congestion 2
 Sleep apnea 1
 Throat clearing 1
Skin
 Skin rash 2
 Skin scratching/picking 3