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Fig. 5 | Molecular Autism

Fig. 5

From: Intranasal administration of exosomes derived from mesenchymal stem cells ameliorates autistic-like behaviors of BTBR mice

Fig. 5

Comparison between MSC-exo and MSC labeled with PKH26 visualization in the brain. a From left to right: MSC-exo intranasal, MSC-exo intravenous, MSC intranasal, and MSC intravenous. MSC-exo cross the blood brain barrier, both intranasally and intravenously, while MSC much less. b Immunostaining of neurons, DAPI and PKH26 labeled MSC-exo after intranasal administration. c Sagittal section of the BTBR MSC-exo brain after intranasal administration of PKH26 labeled MSC-exo (top) and Alan brain atlas (bottom)

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