Fig. 5
From: Subcellular organization of UBE3A in human cerebral cortex
UBE3A expression in neuroglia in temporal cortex from human biopsy specimen. a, b Double labeling reveals UBE3A in the nuclei and somata of Olig2-positive glia (oligodendrocytes, arrowheads). However, UBE3A staining in Olig2-positive glia (b, arrowhead) is appears weaker than in neurons (b, arrow). c Double labeling reveals UBE3A in the nuclei and somata in GFAP-positive cells (astrocytes). UBE3A in GFAP-positive cells is at lower levels than in neurons and Olig2-positive glia. Tissue from case no. Q1010. Scale bar = 50 μm in a, 10 μm in b and c, and 5 μm in d