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Fig. 5 | Molecular Autism

Fig. 5

From: Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models

Fig. 5

Clustering models by log2FC matrices. a Principal component analysis of all genotypes/tissue types. Each group is plotted by its PC1 and PC2 values. Points are colored by HCPC clustering show in B. b HCPC clustering of ASD models. Based on the inertia gained by cutting at each level (inset graph), the HCPC program suggested clustering into four groups as shown. Numbers at the branch points show the approximately unbiased (AU) p value calculated by multiscale bootstrap resampling; clusters with AU greater than 95 are strongly supported by the data. Model identifiers in blue represent hippocampal tissue, red cortical tissue. Gray bars indicate the potential confounding factors of age and background strain (see Table 2)

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