Compound | EC50 [M] | Emax | LC50 [M] |
---|---|---|---|
Topotecan | 3.04E−08 (± 3.40E−09) | 1.51 (± 0.11) | 2.30E−06 (± 2.01E−08) |
Indotecan | 2.56E−08 (± 1.05E−09)* | 1.78 (± 0.13)* | 2.01E−06 (± 1.59E−07) |
Indimitecan | 7.47E−09 (± 7.49E−10)* | 1.47 (± 0.10) | 7.89E−07 (± 3.43E−08)* |
DB-IV-58 | 3.10E−08 (± 9.75E−09) | 1.45 (± 0.12) | 2.01E−06 (± 1.09E−07) |
DB-V-37 | 2.99E−08 (± 8.29E−09) | 1.48 (± 0.08) | 2.02E−06 (± 1.02E−07) |