Skip to main content
Fig. 7 | Molecular Autism

Fig. 7

From: Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells

Fig. 7

PIP2 levels in neuronal cells by quantitative ICC. The relative level of PIP2 was normalized against a nuclear marker. The LS100/LS200 set was carried out on NPCs, while the analysis of the LS300/LS400 and 690KO/690C sets were carried out on day 14 neurons. The asterisk denotes statistical significance using the Student’s t test, two-tailed: LS100 and LS200; p = 0.025, LS300 and LS400; p = 0.003, 690C and 690KO; p = 0.0001. Error bars are standard deviations. A single NPC or neuronal induction was carried out for each set, with between 88 and 128 cells quantified for each

Back to article page

Molecular Autism

ISSN: 2040-2392