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Fig. 4 | Molecular Autism

Fig. 4

From: Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells

Fig. 4

Immunocytochemistry showing F-actin expression in NPCs. a. F-actin staining pattern in control NPCs (LS200, LS400, and LS600) nicely outlines the cytoskeleton, while the expression pattern in the patient samples (LS100, LS300, and LS500) is amorphous. Cytoskeletal outline is seen in both 690C and 690KO NPCs. F-actin staining pattern observed in duplicate samples. b. F-actin expression by quantitative immunocytochemistry. Asterisk indicates p < 0.05 using Student’s t test, two-tailed. Error bars are standard deviations

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