Fig. 6

Postnatal resveratrol treatment ameliorates prenatal norethindrone exposure-induced autism-like behavior through ERβ activation. The 8-week-old male offspring from VEH or NET group received either empty (EMP) or ERβ knockdown (shERβ) lentivirus infusion and were treated by either control (CTL) or resveratrol (RSV) for 4 weeks, and the offspring were sacrificed at 13 weeks of age for further analysis. a–c The amygdala tissues were isolated from 13-week-old treated male offspring for gene expression analysis. a The mRNA levels for gene expression, n = 4. b The quantitation of protein levels, n = 5. c Representative bands for western blots. d Buried marble tests, n = 9. e Interaction time, n = 9. *, P < 0.05, vs VEH/EMP/CTL group; ¶, P < 0.05, vs NET/EMP/CTL group; #, P < 0.05, vs NET/EMP/RSV group. Results are expressed as mean ± SEM