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Fig. 4 | Molecular Autism

Fig. 4

From: Resveratrol ameliorates prenatal progestin exposure-induced autism-like behavior through ERβ activation

Fig. 4

Postnatal resveratrol treatment ameliorates prenatal norethindrone exposure-induced oxidative stress, dysfunction of mitochondria, and lipid metabolism. a–h The amygdala tissues were isolated from 10-week-old male/female offspring for further analysis. a In vivo superoxide anion release, n = 5. b Quantitation of 3-nitrotyrosine (3-NT) formation, n = 5. c 8-OHdG formation, n = 5. d Representative γH2AX western blotting band for both male (upper panel) and female (down panel) offspring. e Quantitation of γH2AX formation for d, n = 5. f Mitochondrial DNA copies, n = 4. g Intracellular ATP levels, n = 5. h The in vivo palmitate oxidation rate, n = 5. i The amygdala neurons were isolated from 10-week-old male/female offspring for in vitro 14C-OA fatty acid uptake, n = 5. *, P < 0.05, vs VEH/CTL group; ¶, P < 0.05, vs NET/CTL group. Results are expressed as mean ± SEM

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