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Fig. 3 | Molecular Autism

Fig. 3

From: Resveratrol ameliorates prenatal progestin exposure-induced autism-like behavior through ERβ activation

Fig. 3

Postnatal resveratrol treatment diminishes prenatal norethindrone exposure-induced methylation of DNA and histone on the ERβ promoter. The amygdala neurons were isolated from 10-week-old male/female offspring for in vitro cell culture analysis. a The representative bands for ERβ methylation in amygdala neurons from both male (upper panel) and female (lower panel) offspring. b DNA methylation on ERβ by real-time PCR-based methylation-specific PCR (MSP) analysis in amygdala neurons, n = 5. c ChIP analysis on the ERβ promoter in male amygdala neurons, n = 5. d ChIP analysis on the ERβ promoter in female amygdala neurons, n = 5. *, P < 0.05, vs VEH/CTL group; ¶, P < 0.05, vs NET/CTL group. Results are expressed as mean ± SEM

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