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Table 4 Enrichment statistics for meQTL targets in ASD-related CpG sites

From: Case-control meta-analysis of blood DNA methylation and autism spectrum disorder

   meQTL p value thresholdb
Permissivec Intermediated Stringente
ASD EWAS p valuea 1 × 10−3 1.20 (0.041) 1.11 (0.218) 1.11 (0.243)
1 × 10−4 1.46 (0.134) 1.71 (0.089) 1.50 (0.205)
  1. Enrichment fold statistics and p values based on 1000 permutations are reported
  2. aASD to DNAm association p value defined from meta-analysis
  3. bSNP to CpG association p value thresholds
  4. cp values in each methylation processing batch that allowed for 100% power to detect a 5% methylation difference with each addition of minor allele (see “Methods”)
  5. dp values in each methylation processing batch that allowed for 90% power to detect same methylation difference
  6. ep values in each methylation processing batch that allowed for 80% power to detect same methylation difference