Fig. 3
From: Sociability deficits after prenatal exposure to valproic acid are rescued by early social enrichment
Mice prenatally exposed to VPA show reduced exploration and increased levels of depression-related behavior. a, b Distance traveled in the closed arms (a) and number of rearings (b) in the EPM. c, d Total distance traveled (c) and time spent grooming (d) in the OF. e, f Total distance traveled (e) and time spent (f) in the lit compartment in the LD box. g, h Time spent immobile in 1-min bins (g) and accumulated time (h) in the TST. i, j Time spent immobile in 1-min bins (i) and cumulative time between 3 and 6 min (j) in the FST. Two-way or repeated measures ANOVA prenatal effect, #p < 0.05, ##p < 0.01, ###p < 0.001. Tukey’s post hoc test, *p < 0.05, **p < 0.01. Graphs indicate means + s.e.m. Detailed statistical information is available in Additional file 1: Table S2