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Table 4 Adjusted associations between prenatal mercury and offspring diagnosed autism and extreme levels of autistic traits. Odds ratios [95%CI] adjusted for maternal age, family adversity index, prenatal life events, smoking and alcohol in pregnancy, maternal locus of control, and maternal education

From: Prenatal mercury exposure and features of autism: a prospective population study

Proxy for Hg exposurea Diagnosed autism, OR [95% CI] Autistic trait, OR [95% CI]
Poor social cognition Poor sociability Poor coherence Repetitive behavior
White fish 1.39 [0.80, 2.40] 0.85 [0.71 ,1.03] 0.93 [0.77, 1.11] 0.90 [0.78, 1.04] 1.01 [0.88, 1.16]
  (P = 0.238) (P = 0.092) (P = 0.399) (P = 0.163) (P = 0.886)
Oily fish 1.00 [0.68, 1.47] 0.98 [0.84, 1.14] 0.90 [0.78, 1.04] 1.01 [0.90, 1.14] 1.03 [0.92, 1.15]
  (P = 0.994) (P = 0.774) (P = 0.150) (P = 0.853) (P = 0.613)
Shellfish 0.86 [0.54, 1.38] 0.92 [0.77, 1.11] 0.91 [0.76, 1.08] 0.94 [0.81, 1.08] 1.03 [0.90, 1.17]
  (P = 0.542) (P = 0.401) (P = 0.284) (P = 0.351) (P = 0.707)
Amalgam inserted 0.62 [0.37, 1.03] 0.99 [0.83, 1.18] 1.14 [0.97, 1.34] 1.07 [0.94, 1.22] 1.02 [0.90, 1.16]
  (P = 0.067) (P = 0.905) (P = 0.119) (P = 0.320) (P = 0.761)
Amalgam extracted 0.47 [0.24, 0.93] 1.09 [0.89, 1.33] 1.14 [0.94, 1.38] 1.10 [0.94, 1.28] 1.04 [0.89, 1.20]
  (P = 0.031) (P = 0.424) (P = 0.178) (P = 0.237) (P = 0.647)
No. of amalgam fillings 0.96 [0.76, 1.21] 1.00 [0.91, 1.09] 0.91 [0.84, 0.99] 1.01 [0.94, 1.09] 0.95 [0.89, 1.01]
  (P = 0.730) (P = 0.965) (P = 0.033) (P = 0.790) (P = 0.122)
No. in analyses 7498–10,452 5888–6972 7119–8512 5646–6690 6302–7477
  1. All associations with P < 0.10 are italicized
  2. aCategorization of variables as shown in Table 3. Significance levels calculated testing for a linear trend