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Fig. 1 | Molecular Autism

Fig. 1

From: Integrated genome-wide Alu methylation and transcriptome profiling analyses reveal novel epigenetic regulatory networks associated with autism spectrum disorder

Fig. 1

Schematic diagram of experimental workflow. Our workflow initiated with the acquisition of blood-based gene expression profiles from GEO DataSets and human Alu-inserted gene lists. Fisher’s exact test was then used to identify differentially expressed genes (DEGs) with Alu insertions. A total of 320 overlapping genes among the selected study results were used to predict biological functions, diseases, and gene regulatory networks. Fifty-six LCLs were used as a model to investigate the association between the Alu methylation status and Alu expression profiles in LCLs

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