Fig. 7From: Impairment of social behaviors in Arhgef10 knockout miceMAO-A is decreased in Arhgef10 −/− mice. The main degradation enzymes 5-HT and NE were analyzed by Western blotting. a MAO-A expression was decreased in the frontal cortex and amygdala of Arhgef10 −/− mice. Another metabolizing enzyme, MOA-B, did not show a significant difference between WT and KO mice b. The main enzymes for the synthesis of the amine neurotransmitters were also analyzed by Western blotting. The protein levels of both DBH c and TPH d were similar between WT and KO mice in the examined brain areas. *p < 0.05 compared with WT. MAO-A monoamine oxidase A, MAO-B monoamine oxidase B, DBH dopamine β-hydroxylase, TPH tryptophan hydroxylaseBack to article page