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Fig. 2 | Molecular Autism

Fig. 2

From: Insulin receptor sensitization restores neocortical excitation/inhibition balance in a mouse model of autism

Fig. 2

Insulin-induced increased inhibition. ac Example records of GABAA receptor-mediated sIPSCs. HP holding potential. d Cumulative fraction curves of the sIPSC amplitudes show that the amplitude distribution for insulin (WT I) and insulin + pioglitazone (WT I + P) are shifted to the right (larger amplitude), indicating that both conditions increase the amplitude of sIPSCs compared to no drug controls. e The average amplitude of sIPSCs is higher with either drug application condition compared to the controls, but not different between the two drug application conditions. Box and whisker plots showing the population distribution

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