Table 1 Overview of analysis strategies
From: Network-specific sex differentiation of intrinsic brain function in males with autism
Strategy | Description of overlapping maps | Addressed potential confounds | Samples |
|---|---|---|---|
Strategy 1 Originally published Z-maps | Z-maps obtained from original ABIDE I and FCP samples | – | ABIDE I: N = 763 (ASD = 360; NT = 403) FCP: N = 828 (NT M = 357; NT F = 471) |
Strategy 2 Adjusting analytical pipelines | Z-maps obtained after aligning processing with samples similar to strategy 1 | Differences in MRI analytical methods (i.e., preprocessing and group model) | ABIDE I: N = 759 (ASD = 356; NT = 403) FCP: N = 824 (NT M = 356; NT F = 468) |
Strategy 3 Adjusting age | Z-maps obtained in age-matched ABIDE I and FCP subsamples | Differences in sample age and MRI analytical methods | ABIDE I: N = 199 (ASD = 93; NT = 106) FCP: N = 439 (NT M = 183; NT F = 256) |
Strategy 4 Independent NT sample | Z-maps of ABIDE I subsample as strategy 3 and an independent sex difference sample from Brain Genomics Superstruct Project (GSP) | Differences in sample age and MRI analytical methods | ABIDE I: N = 199 (ASD = 93; NT = 106) GSP: N = 742 (NT M = 320; NT F = 422) |