Fig. 1
From: Network-specific sex differentiation of intrinsic brain function in males with autism
Spatial overlap scenarios. Depending on the combination of statistical contrasts being overlapped, four different scenarios can emerge. Decreases or increases of R-fMRI metrics in males with autism spectrum disorder (ASD) relative to neurotypical males (NT M) lead to different scenarios depending on whether they overlap with increases or decreases in NT M relative to NT females (F) (gray boxes). Following the predictions of the Extreme Male Brain (EMB) theory and Gender Incoherence (GI) theory, two scenarios fit the EMB model predicting a shift-towards-maleness (STM) in males with ASD (see blue and turquois boxes) and two scenarios fit the GI model predicting a shift-towards-femaleness (STF) in males with ASD (see orange and yellow boxes)