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Table 5 Renal clearance of glycation, oxidation, and nitration free adducts

From: Advanced glycation endproducts, dityrosine and arginine transporter dysfunction in autism - a source of biomarkers for clinical diagnosis

Amino acid Renal clearance (μL/mg creatinine)  
Healthy controls ASD P value
FL# 0.696 (0.375–1.16) 0.866 (0.384–2.31)  
CML 0.297 (0.249–0.387) 0.259 (0.171–0.782)  
CEL 0.0068 (0.003–0.019) 0.0042 (0.002–0.011)  
G-H1 21.2 (13.1–34.7) 23.9 (15.0–57.7)  
MG-H1# 0.718 (0.496–1.04) 0.628 (0.363–0.912)  
3DG-H 0.067 (0.033–0.163) 0.087 (0.042–0.131)  
CMA 1.57 (0.997–2.08) 0.791 (0.465–1.36) 0.0011*
GSP 0.121 (0.083–0.274) 0.112 (0.067–0.195)  
MOLD 0.214 (0.075–0.487) 0.269 (0.153–0.656)  
Pyrraline 0.81 (0.58–1.17) 1.07 (0.64–1.96)  
DT 0.119 (0.657–2.02) 0.747 (0.545–0.107) 0.0025
NFK 0.062 (0.038–0.109) 0.096 (0.049–0.139) 0.030
GSA 29.9 (11.1–45.8) 17.8 (1.96–26.1)  
3-NT 0.068 (0.034–0.100) 0.042 (0.036–0.129)  
  1. Data are mean ± SD or median (lower–upper quartile); healthy controls, n = 21, and ASD, n = 27. Significance: t-test for parametric data and Mann-Whitney U for non-parametric data
  2. *P < 0.05, after Bonferroni correction of 14 applied
  3. #mL/mg creatinine