|
Amino acid
|
Renal clearance (μL/mg creatinine)
| |
|---|
|
Healthy controls
|
ASD
|
P value
|
|---|
|
FL#
|
0.696 (0.375–1.16)
|
0.866 (0.384–2.31)
| |
|
CML
|
0.297 (0.249–0.387)
|
0.259 (0.171–0.782)
| |
|
CEL
|
0.0068 (0.003–0.019)
|
0.0042 (0.002–0.011)
| |
|
G-H1
|
21.2 (13.1–34.7)
|
23.9 (15.0–57.7)
| |
|
MG-H1#
|
0.718 (0.496–1.04)
|
0.628 (0.363–0.912)
| |
|
3DG-H
|
0.067 (0.033–0.163)
|
0.087 (0.042–0.131)
| |
|
CMA
|
1.57 (0.997–2.08)
|
0.791 (0.465–1.36)
|
0.0011*
|
|
GSP
|
0.121 (0.083–0.274)
|
0.112 (0.067–0.195)
| |
|
MOLD
|
0.214 (0.075–0.487)
|
0.269 (0.153–0.656)
| |
|
Pyrraline
|
0.81 (0.58–1.17)
|
1.07 (0.64–1.96)
| |
|
DT
|
0.119 (0.657–2.02)
|
0.747 (0.545–0.107)
|
0.0025
|
|
NFK
|
0.062 (0.038–0.109)
|
0.096 (0.049–0.139)
|
0.030
|
|
GSA
|
29.9 (11.1–45.8)
|
17.8 (1.96–26.1)
| |
|
3-NT
|
0.068 (0.034–0.100)
|
0.042 (0.036–0.129)
| |
- Data are mean ± SD or median (lower–upper quartile); healthy controls, n = 21, and ASD, n = 27. Significance: t-test for parametric data and Mann-Whitney U for non-parametric data
- *P < 0.05, after Bonferroni correction of 14 applied
- #mL/mg creatinine
