|
Glycation markers
|
Healthy controls
|
ASD
|
P value
|
|---|
|
FL (mmol/mol lys)
|
1.27 ± 0.39
|
1.41 ± 0.53
|
NS
|
|
CML (mmol/mol lys)
|
0.158 ± 0.026
|
0.190 ± 0.038
|
0.0018*
|
|
CEL (mmol/mol lys)
|
0.117 ± 0.044
|
0.092 ± 0.054
|
NS
|
|
G-H1 (mmol/mol arg)
|
0.012 ± 0.005
|
0.016 ± 0.011
|
NS
|
|
MG-H1 (mmol/mol arg)
|
0.473 ± 0.074
|
0.535 ± 0.100
|
0.021
|
|
3DG-H (mmol/mol arg)
|
0.165 ± 0.037
|
0.138 ± 0.027
|
0.0052
|
|
CMA (mmol/mol arg)
|
0.054 (0.043–0.067)
|
0.077 (0.066–0.101)
|
0.000082**
|
|
MOLD (mmol/mol lys)
|
0.027 ± 0.011
|
0.025 ± 0.016
|
NS
|
|
GSP (mmol/mol lys)
|
0.514 ± 0.111
|
0.571 ± 0.206
|
NS
|
|
DT (mmol/mol tyr)
|
0.025 (0.019–0.031)
|
0.047 (0.035–0.094)
|
0.000012***
|
|
NFK (mmol/mol trp)
|
15.6 ± 1.7
|
15.0 ± 1.5
|
NS
|
|
AASA (mmol/mol lys)
|
0.154 ± 0.048
|
0.152 ± 0.081
|
NS
|
|
GSA (mmol/mol arg)
|
0.639 ± 0.327
|
0.713 ± 0.350
|
NS
|
|
3-NT (mmol/mol tyr)
|
0.0056 (0.0045–0.0069)
|
0.0053 (0.0045–0.0064)
|
NS
|
- Data are median (lower–upper quartile); healthy controls, n = 21, and ASD, n = 27. Significance (Mann–Whitney U)
- *P < 0.05, **P < 0.01, and ***P < 0.001 after Bonferroni correction of 14 applied
