No preliminary evidence of differences in astrocyte density within the white matter of the dorsolateral prefrontal cortex in autism

Lee, Ting Ting; Skafidas, Efstratios; Dottori, Mirella; Zantomio, Daniela; Pantelis, Christos; Everall, Ian; Chana, Gursharan

doi:10.1186/s13229-017-0181-5

Molecular Autism

Table 2 Statistical analysis of normality test, correlation test, and group comparison between autism and control

From: No preliminary evidence of differences in astrocyte density within the white matter of the dorsolateral prefrontal cortex in autism

	Diagnosis	Shapiro-Wilk normality test			Correlation age		Correlation PMI		Group differences (ASD vs control)
	Diagnosis	Statistic	df	Sig.	Pearson (r)	Spearman (rho)	Pearson (r)	Spearman (rho)	Mean	SE	p value
Age	ASD	0.907	8	0.335					24.612	5.803	0.604^a
Age	Control	0.907	7	0.374					20.092	6.204	0.604^a
PMI (h)	ASD	0.864	8	0.133					25.625	5.673	0.132^a
PMI (h)	Control	0.954	7	0.766					12.286	6.065	0.132^a
Population (all glia)	ASD	0.950	8	0.715	0.205 (p = 0.463)		− 0.390 (p = 0.150)		2,401,704.83	121,494.58	0.415^a
Population (all glia)	Control	0.873	7	0.196	0.205 (p = 0.463)		− 0.390 (p = 0.150)		2,351,803.21	129,883.17	0.415^a
Population (astrocyte)	ASD	0.969	8	0.894	− 0.267 (p = 0.337)		0.168 (p = 0.549)		100,669.51	8557.62	0.202^a
Population (astrocyte)	Control	0.978	7	0.949	− 0.267 (p = 0.337)		0.168 (p = 0.549)		117,513.34	9148.48	0.202^a
Population (other glia)	ASD	0.951	8	0.718	0.219 (p = 0.433)		− 0.392 (p = 0.149)		2,401,035.25	124,249.39	0.376^a
Population (other glia)	Control	0.868	7	0.178	0.219 (p = 0.433)		− 0.392 (p = 0.149)		2,234,289.88	132,828.19	0.376^a
Nucleator (area)	ASD	0.791	8	0.023		− 0.093 (p = 0.742)		− 0.118 (p = 0.676)	92.475	4.556	0.397^b
Nucleator (area)	Control	0.866	7	0.170		− 0.093 (p = 0.742)		− 0.118 (p = 0.676)	87.423	4.870	0.397^b
Spaceballs length (all) (um)	ASD	0.901	8	0.298	− 0.289 (p = 0.296)		− 0.206 (p = 0.461)		51,228,155.8	6,563,846.09	0.923^a
Spaceballs length (all) (um)	Control	0.982	7	0.970	− 0.289 (p = 0.296)		− 0.206 (p = 0.461)		52,176,610.3	7,017,046.63	0.923^a
IOD (mean)	ASD	0.938	8	0.591	− 0.681 (p = 0.007)		− 0.517 (p = 0.059)		143.083	4.159	0.066^c
IOD (mean)	Control	0.922	7	0.487	− 0.681 (p = 0.007)		− 0.517 (p = 0.059)		156.127	4.809	0.066^c

^aGeneral linear model
^bNon-parametric independent sample t test
^cGeneral linear model with covariate “age”

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