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Table 4 Adjusted slope for Age, Severity and SRS

From: Cytokine levels and associations with symptom severity in male and female children with autism spectrum disorder

  Age Severity SRS
  Male Female Male Female Male Female
Analyte Slope Pr(>Chisq) Slope Pr(>Chisq) Slope Pr(>Chisq) Slope Pr(>Chisq) Slope Pr(>Chisq) Slope Pr(>Chisq)
Basic FGF − 0.01 0.89 0.00 0.98 − 0.04 0.39 − 0.06 0.37 0.00 0.97 0.00 0.97
Eotaxin − 0.03 0.16 − 0.02 0.77 − 0.06 0.13 − 0.11 0.07 0.00 0.97 −0.01 0.85
G-CSF 0.02 0.48 0.04 0.55 −0.03 0.48 − 0.03 0.68 0.01 0.96 0.00 0.97
GM-CSF − 0.01 0.85 0.02 0.85 −0.01 0.89 − 0.01 0.87 0.01 0.96 0.00 0.98
IFN-γ − 0.02 0.77 0.00 0.98 − 0.04 0.34 − 0.07 0.35 0.00 0.97 − 0.01 0.97
IL-10 − 0.03 0.16 − 0.02 0.85 − 0.01 0.89 − 0.08 0.22 − 0.01 0.90 − 0.01 0.97
IL-12p70 −0.04 0.07 0.00 0.98 − 0.02 0.68 − 0.12 0.05 −0.01 0.88 0.00 0.97
IL-13 0.01 0.77 − 0.01 0.89 − 0.01 0.75 − 0.05 0.44 0.00 0.97 − 0.01 0.70
IL-15 0.04 0.04* 0.04 0.48 0.00 0.96 0.04 0.54 0.00 0.97 0.00 0.97
IL-17A − 0.02 0.77 0.00 0.99 − 0.03 0.48 − 0.04 0.54 0.00 0.97 0.00 0.97
IL-1β − 0.02 0.72 0.02 0.85 −0.06 0.15 − 0.20 < 0.001* −0.01 0.88 0.01 0.85
IL-1RA − 0.01 0.85 0.02 0.77 − 0.04 0.35 − 0.08 0.22 0.00 0.97 0.00 0.97
IL-2 0.00 0.98 0.01 0.87 0.00 1.00 −0.04 0.57 0.00 0.97 0.00 0.97
IL-4 0.00 0.98 0.01 0.87 −0.04 0.37 −0.07 0.31 0.00 0.97 0.00 0.97
IL-5 − 0.02 0.77 0.00 0.98 − 0.05 0.22 − 0.06 0.39 0.00 0.97 − 0.01 0.85
IL-6 − 0.01 0.84 0.02 0.85 − 0.04 0.39 − 0.06 0.39 0.00 0.97 0.00 0.97
IL-7 0.00 0.95 0.01 0.98 − 0.04 0.34 − 0.06 0.35 0.00 0.97 0.00 0.97
IL-8 − 0.06 0.01* 0.02 0.77 − 0.05 0.22 − 0.29 < 0.001* 0.00 0.97 0.02 0.03*
IL-9 − 0.01 0.85 0.00 0.98 − 0.01 0.74 0.00 1.00 − 0.01 0.90 0.00 0.97
IP-10 − 0.04 0.09 − 0.10 0.001* − 0.05 0.22 − 0.02 0.74 − 0.01 0.80 − 0.02 0.21
MCP-1 0.01 0.91 0.02 0.84 − 0.03 0.48 − 0.05 0.48 0.00 0.97 0.00 0.97
MIP-1α − 0.01 0.84 − 0.01 0.89 − 0.03 0.48 − 0.03 0.60 0.00 0.97 0.00 0.97
MIP-1β − 0.05 0.01* − 0.03 0.63 − 0.01 0.75 − 0.16 0.01* − 0.01 0.85 0.01 0.97
PDGF-BB − 0.04 0.08 − 0.02 0.85 − 0.08 0.03* − 0.16 0.01* −0.01 0.80 0.01 0.85
RANTES − 0.01 0.88 0.01 0.87 − 0.02 0.54 − 0.09 0.20 0.00 0.97 0.01 0.85
TNF-α −0.02 0.72 0.00 0.99 − 0.05 0.22 − 0.05 0.44 0.00 0.97 0.00 0.97
VEGF − 0.04 0.09 0.01 0.98 − 0.03 0.48 − 0.13 0.03* 0.00 0.97 0.00 0.97
  1. Chisq tests: p value adjustment method: false discovery rate
  2. Abbreviations: Basic.FGF basic fibroblast growth factor, G.CSF granulocyte colony-stimulating factor, GM granulocyte macrophage colony-stimulating factor, IFN. γ interferon-γ, IL interleukin, IL.1β IL-1 beta, IL.1RA, IL-1 receptor antagonist, IP interferon gamma-inducible protein 10, MCP.1 monocyte chemotactic protein-1, MIP.1α macrophage inflammatory protein-1α, MIP.1β macrophage inflammatory protein-1β, PDGF.BB Platelet derived growth factor-BB, RANTES regulated on activation, normal T cell expressed and secreted, TNF. α tumor necrosis factor-α, VEGF vascular endothelial growth factor. * indicates significant difference at P < 0.05 or better