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Table 4 Adjusted slope for Age, Severity and SRS

From: Cytokine levels and associations with symptom severity in male and female children with autism spectrum disorder

 

Age

Severity

SRS

 

Male

Female

Male

Female

Male

Female

Analyte

Slope

Pr(>Chisq)

Slope

Pr(>Chisq)

Slope

Pr(>Chisq)

Slope

Pr(>Chisq)

Slope

Pr(>Chisq)

Slope

Pr(>Chisq)

Basic FGF

− 0.01

0.89

0.00

0.98

− 0.04

0.39

− 0.06

0.37

0.00

0.97

0.00

0.97

Eotaxin

− 0.03

0.16

− 0.02

0.77

− 0.06

0.13

− 0.11

0.07

0.00

0.97

−0.01

0.85

G-CSF

0.02

0.48

0.04

0.55

−0.03

0.48

− 0.03

0.68

0.01

0.96

0.00

0.97

GM-CSF

− 0.01

0.85

0.02

0.85

−0.01

0.89

− 0.01

0.87

0.01

0.96

0.00

0.98

IFN-γ

− 0.02

0.77

0.00

0.98

− 0.04

0.34

− 0.07

0.35

0.00

0.97

− 0.01

0.97

IL-10

− 0.03

0.16

− 0.02

0.85

− 0.01

0.89

− 0.08

0.22

− 0.01

0.90

− 0.01

0.97

IL-12p70

−0.04

0.07

0.00

0.98

− 0.02

0.68

− 0.12

0.05

−0.01

0.88

0.00

0.97

IL-13

0.01

0.77

− 0.01

0.89

− 0.01

0.75

− 0.05

0.44

0.00

0.97

− 0.01

0.70

IL-15

0.04

0.04*

0.04

0.48

0.00

0.96

0.04

0.54

0.00

0.97

0.00

0.97

IL-17A

− 0.02

0.77

0.00

0.99

− 0.03

0.48

− 0.04

0.54

0.00

0.97

0.00

0.97

IL-1β

− 0.02

0.72

0.02

0.85

−0.06

0.15

− 0.20

< 0.001*

−0.01

0.88

0.01

0.85

IL-1RA

− 0.01

0.85

0.02

0.77

− 0.04

0.35

− 0.08

0.22

0.00

0.97

0.00

0.97

IL-2

0.00

0.98

0.01

0.87

0.00

1.00

−0.04

0.57

0.00

0.97

0.00

0.97

IL-4

0.00

0.98

0.01

0.87

−0.04

0.37

−0.07

0.31

0.00

0.97

0.00

0.97

IL-5

− 0.02

0.77

0.00

0.98

− 0.05

0.22

− 0.06

0.39

0.00

0.97

− 0.01

0.85

IL-6

− 0.01

0.84

0.02

0.85

− 0.04

0.39

− 0.06

0.39

0.00

0.97

0.00

0.97

IL-7

0.00

0.95

0.01

0.98

− 0.04

0.34

− 0.06

0.35

0.00

0.97

0.00

0.97

IL-8

− 0.06

0.01*

0.02

0.77

− 0.05

0.22

− 0.29

< 0.001*

0.00

0.97

0.02

0.03*

IL-9

− 0.01

0.85

0.00

0.98

− 0.01

0.74

0.00

1.00

− 0.01

0.90

0.00

0.97

IP-10

− 0.04

0.09

− 0.10

0.001*

− 0.05

0.22

− 0.02

0.74

− 0.01

0.80

− 0.02

0.21

MCP-1

0.01

0.91

0.02

0.84

− 0.03

0.48

− 0.05

0.48

0.00

0.97

0.00

0.97

MIP-1α

− 0.01

0.84

− 0.01

0.89

− 0.03

0.48

− 0.03

0.60

0.00

0.97

0.00

0.97

MIP-1β

− 0.05

0.01*

− 0.03

0.63

− 0.01

0.75

− 0.16

0.01*

− 0.01

0.85

0.01

0.97

PDGF-BB

− 0.04

0.08

− 0.02

0.85

− 0.08

0.03*

− 0.16

0.01*

−0.01

0.80

0.01

0.85

RANTES

− 0.01

0.88

0.01

0.87

− 0.02

0.54

− 0.09

0.20

0.00

0.97

0.01

0.85

TNF-α

−0.02

0.72

0.00

0.99

− 0.05

0.22

− 0.05

0.44

0.00

0.97

0.00

0.97

VEGF

− 0.04

0.09

0.01

0.98

− 0.03

0.48

− 0.13

0.03*

0.00

0.97

0.00

0.97

  1. Chisq tests: p value adjustment method: false discovery rate
  2. Abbreviations: Basic.FGF basic fibroblast growth factor, G.CSF granulocyte colony-stimulating factor, GM granulocyte macrophage colony-stimulating factor, IFN. γ interferon-γ, IL interleukin, IL.1β IL-1 beta, IL.1RA, IL-1 receptor antagonist, IP interferon gamma-inducible protein 10, MCP.1 monocyte chemotactic protein-1, MIP.1α macrophage inflammatory protein-1α, MIP.1β macrophage inflammatory protein-1β, PDGF.BB Platelet derived growth factor-BB, RANTES regulated on activation, normal T cell expressed and secreted, TNF. α tumor necrosis factor-α, VEGF vascular endothelial growth factor. * indicates significant difference at P < 0.05 or better