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Table 3 Significance analysis of interaction effects in cytokine levels and clinical covariates

From: Cytokine levels and associations with symptom severity in male and female children with autism spectrum disorder

 

Combined sex

Males

Females

Effect

Chisq

Df

Pr(>Chisq)

Chisq

Df

Pr(>Chisq)

Chisq

Df

Pr(>Chisq)

(Intercept)

387.78

1

< 0.001

239.73

1

< 0.001

105.51

1

< 0.001

Severity

3.28

1

0.07

1.48

1

0.22

0.88

1

0.35

Age

0.01

1

0.91

0.12

1

0.73

0.44

1

0.51

SRS

0.13

1

0.72

0.06

1

0.81

1.35

1

0.25

Sleep

0.08

1

0.78

0.23

1

0.63

0.38

1

0.54

GI

0.53

1

0.47

0.96

1

0.33

0.25

1

0.62

Analyte

1079.27

26

< 0.001

787.12

26

< 0.001

247.60

26

< 0.001

Severity:analyte

43.64

26

0.02

16.42

26

0.93

71.10

26

< 0.001

Age:analyte

75.23

26

< 0.001

60.36

26

< 0.001

41.61

26

0.03

SRS:analyte

10.96

26

1.00

19.09

26

0.83

40.28

26

0.04

Sleep:analyte

17.09

26

0.91

12.47

26

0.99

28.20

26

0.35

GI:analyte

9.65

26

1.00

13.11

26

0.98

23.97

26

0.58

  1. Analysis of deviance tables (type III Wald chi-square tests) for the statistical model: mY~(severity + age + sex + SRS + sleep + GI)*Analyte + (1|ID). Where mY represents the normalized log2 of the fluorescence responses with respect to run (Additional file 1: Figure S2)
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Molecular Autism

ISSN: 2040-2392