Fig. 1

Optimal network graphs representing cytokine correlations separated for sex. Each node represents a cytokine, and each edge represents a Spearman’s correlation between two cytokines. Green edges indicate positive correlations and red edges represent negative correlations. The width of the edge corresponds to the absolute value of the correlation: the higher the correlation, the thicker and more saturated is the edge. Node abbreviations: B.F basic fibroblast growth factor, Etx eotaxin, G.C granulocyte colony-stimulating factor, GM granulocyte macrophage colony-stimulating factor, IFN interferon-gamma, IL interleukin, IL.1B 1 beta, IL.1r IL-1 receptor antagonist, IL.12 IL-12p70, IL.17 IL-17A, IP interferon gamma-inducible protein 10, MCP monocyte chemotactic protein-1, MIP.1a macrophage inflammatory protein-1 alpha, MIP.1b macrophage inflammatory protein-1 beta, PDG platelet-derived growth factor-BB, RAN regulated on activation, normal T cell expressed and secreted, TNF tumor necrosis factor-alpha, VEG vascular endothelial growth factor