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Table 3 Medical findings in individuals with FOXP1 syndrome

From: Prospective investigation of FOXP1 syndrome

Medical feature S1 S2 S3 S4 S5 W1 W2 W3 W4 Total (%)
Cardiac
 Congenital heart defect +a +b 2/9 (22%)
 Abnormal electrocardiogram n/a n/a n/a + n/a n/a n/a n/a 1/2 (50%)
Sinopulmonary
 Recurrent otitis media + + + + + + 6/9 (67%)
 Recurrent upper respiratory tract infections + + + + 4/9 (44%)
 Neuroendocrine hyperplasia of infancy + 1/9 (11%)
 Pulmonary hypertension + 1/9 (11%)
Urinary tract
 Genitourinary abnormalities + n/a 1/8 (13%)
Endocrine
 Body mass index (percentile for age) 27.8 85.8 69.8 82.1 58.7 20.2 15.4 19.7 n/a  
 Overweight + n/a 1/8 (13%)
 Hypothyroidism + 1/9 (11%)
 Diabetes mellitus + 1/9 (11%)
Other medical
 Constipation + + + + 4/9 (44%)
 Skin infections + + 2/9 (22%)
 Allergies + + 2/9 (22%)
 Iron deficiency + + 2/9 (22%)
 Visual refractive error + + + + + 5/9 (56%)
 Strabismus + + + + + 5/9 (56%)
  1. aPulmonary valve stenosis
  2. bPatent ductus arteriosus discovered at 14 months that resolved without intervention
  3. n/a information not available