Table 4 Group means and effect sizes of group differences on neuropsychiatric questionnaires
From: Critical region within 22q11.2 linked to higher rate of autism spectrum disorder
Number | Mean (SD) | d | 95% confidence interval | |
|---|---|---|---|---|
SRS-2 T score | 50 (10) | |||
BD/CD deletion | 9 | 53.4 (13.6) | ||
AB/AC deletion | 10 | 68.5 (15.7) | 1.01 | (− 0.07, 2.11) |
Classic deletion | 61 | 63.0 (12.6) | − 0.41 | (− 1.11, 0.27) |
BD/CD duplication | 6 | 59.5 (16.6) | ||
Classic duplication | 28 | 64.0 (16.3) | 0.27 | (− 0.67, 1.22) |
SCQ raw total | Cutoff 15 | |||
BD/CD deletion | 7 | 5.7 (4.9) | ||
AB/AC deletion | 8 | 15.0 (9.3) | 1.20 | (− 0.11, 2.52) |
Classic deletion | 52 | 10.8 (7.3) | − 0.54 | (− 1.32, 0.23) |
BD/CD duplication | 4 | 7.2 (9.5) | ||
Classic duplication | 22 | 12.4 (10.3) | 0.50 | (− 0.67, 1.68) |
Vineland composite | 100(15) | |||
BD/CD deletion | 5 | 103.8 (19.6) | ||
AB/AC deletion | 10 | 85.7 (24.0) | − 0.79 | (− 2.11, 0.52) |
Classic deletion | 57 | 87.1 (15.9) | 0.08 | (− 0.61, 0.78) |
BD/CD duplication | 6 | 92.6 (18.7) | ||
Classic duplication | 27 | 89.4 (19.4) | − 0.16 | (− 1.11, 0.78) |
Vineland communication | 100(15) | |||
BD/CD deletion | 5 | 106.0 (21.7) | ||
AB/AC deletion | 10 | 83.0 (18.5) | − 1.17 | (− 2.55, 0.20) |
Classic deletion | 58 | 89.7 (18.1) | 0.36 | (− 0.32, 1.06) |
BD/CD duplication | 6 | 92.1 (20.2) | ||
Classic duplication | 27 | 91.2 (18.5) | − 0.04 | (− 0.99, 0.90) |
Vineland daily living | 100(15) | |||
BD/CD deletion | 5 | 96.4 (14.6) | ||
AB/AC deletion | 10 | 86.9 (26.2) | − 0.40 | (− 1.69, 0.87) |
Classic deletion | 57 | 88.4 (15.1) | 0.08 | (− 0.60, 0.78) |
BD/CD duplication | 6 | 91.8 (23.0) | ||
Classic duplication | 28 | 93.6 (21.2) | 0.08 | (− 0.86, 1.02) |
Vineland socialization | 100(15) | |||
BD/CD deletion | 5 | 107.6 (19.6) | ||
AB/AC deletion | 10 | 91.0 (27.4) | − 0.65 | (− 1.96, 0.65) |
Classic deletion | 57 | 90.1 (16.5) | − 0.04 | (− 0.74, 0.64) |
BD/CD duplication | 6 | 98.1 (18.3) | ||
Classic duplication | 27 | 90.8 (21.2) | − 0.35 | (− 1.30, 0.60) |
CASI ADHD | ||||
BD/CD deletion | 2 | 2.5 (1.3) | ||
AB/AC deletion | 7 | 3.4 (1.4) | 0.63 | (− 1.56, 2.83) |
Classic deletion | 43 | 2.7 (1.2) | − 0.52 | (− 1.36, 0.32) |
BD/CD duplication | 4 | 2.7 (2.1) | ||
Classic duplication | 20 | 2.8 (1.3) | 0.09 | (− 1.09, 1.27) |
CASI anxiety | ||||
BD/CD deletion | 2 | 1.3 (0.7) | ||
AB/AC deletion | 7 | 1.9 (1.1) | 0.49 | (− 1.68, 2.67) |
Classic deletion | 43 | 2.3 (1.3) | 0.30 | (− 0.53, 1.14) |
BD/CD duplication | 4 | 1.9 (1.5) | ||
Classic duplication | 20 | 1.8 (1.6) | − 0.05 | (− 1.24, 1.12) |
CASI ASD | ||||
BD/CD deletion | 1 | n/a | ||
AB/AC deletion | 4 | 1.0 (1.0) | n/a | n/a |
Classic deletion | 37 | 0.5 (0.4) | − 0.83 | (− 1.94, 0.27) |
BD/CD duplication | 4 | 0.6 (0.4) | ||
Classic duplication | 16 | 0.8 (0.8) | 0.26 | (− 0.98, 1.50) |
CASI Schizoaffective | ||||
BD/CD deletion | 1 | n/a | ||
AB/AC deletion | 3 | 0.5(0.5) | n/a | n/a |
Classic deletion | 6 | 0.5(0.2) | − 0.09 | (− 0.78, 0.61) |
BD/CD duplication | 0 | n/a | ||
Classic duplication | 4 | 0.5(0.2) | n/a | n/a |
CASI behav. regulation | ||||
BD/CD deletion | 2 | 0.9 (0.4) | ||
AB/AC deletion | 7 | 0.9 (0.6) | 0.06 | (− 2.08, 2.21) |
Classic deletion | 43 | 1.0 (0.6) | 0.16 | (− 0.67, 1.00) |
BD/CD duplication | 4 | 0.3 (0.3) | ||
Classic duplication | 20 | 1.0 (0.8) | 0.78 | (− 0.42, 2.00) |
CASI Depression | ||||
BD/CD deletion | 2 | 0.4 (0) | ||
AB/AC deletion | 7 | 0.6 (0.7) | 0.33 | (− 1.82, 2.50) |
Classic deletion | 43 | 0.5 (0.7) | − 0.15 | (− 0.99, 0.67) |
BD/CD duplication | 4 | 0.2 (0.4) | ||
Classic duplication | 20 | 0.4 (0.4) | 0.48 | (− 0.70, 1.68) |