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Table 3 ASD rates among probands

From: Critical region within 22q11.2 linked to higher rate of autism spectrum disorder

Region

Number

n ASD (male)

% de novoa

Age mean (sd)

Age range (years)

% male

AB/AC deletion group

12

5(3)

90%

10.0 (4.4)

5–18

58%

 A-B deletion

9

4(3)

90%

8.7 (3.7)

5–15

67%

 A-C deletion

3

1(0)

100%

13.7 (4.8)

9–18

33%

BD/CD deletion group

8

0

60%

10.5 (4.8)

5–18

25%

 B-D deletion

6

0

70%

10.2 (3.8)

6–17

17%

 C-D deletion

2

0

0%

11.6 (9.1)

5–18

50%

Classic AD duplication

29

7(5)

67%

7.1 (3.4)

2–13

75%

BD/CD duplication group

5

1(0)

30%

12.7 (10.4)

5–31

60%

 B-D duplication

3

1(0)

0%

15.8 (13.1)

7–31

67%

 C-D duplication

2

0

50%

8.0 (4.1)

5–11

50%

  1. Participant characteristics and autism diagnosis for all probands with a nested deletion of 22q11.2. Individuals harboring an AB or AC deletion presented with ASD at a rate of 41.6% (5 of 12). Case studies are excluded from this table
  2. aPercentage of individuals with known inheritance