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Table 2 Descriptive statistics from the 7-year visit RB

From: Neurocognitive and observational markers: prediction of autism spectrum disorder from infancy to mid-childhood

 

Low risk

High-risk No ASD

High-risk ASD

Group differences

Age (months)

 Mean (SD)

89.34 (4.81)

91.42 (6.28)

89.13 (6.53)

n/s

  N (girls)

35* (21)

24 (19)

15 (8)

ADI-social

 Mean (SD)

Not completed

4.04 (5.48)

13.14 (4.69)

t(36) = − 5.20, p < 0.001

  N (girls)

24 (19)

14 (8)

ADI communication

 Mean (SD)

Not completed

4.25 (4.67)

10.43 (4.59)

t(36) = − 3.96, p < 0.001

  N (girls)

24 (19)

14 (8)

ADI RRB

 Mean (SD)

Not completed

0.58 (1.41)

3.57 (1.74)

t(36) = − 5.77, p < 0.001

  N (girls)

24 (19)

14 (8)

ADOS CSS total

 Mean (SD)

1.70 (1.19)

2.46 (1.41)

6.20 (2.78)

F(2, 69) = 37.35, p < 0.001, η 2 = 0.520

  N (girls)

33 (19)

24 (19)

15 (8)

ADOS CSS SA

 Mean (SD)

2.18 (1.70)

2.96 (1.60)

6.60 (2.59)

F(2, 69) = 29.11, p < 0.001, η 2 = 0.458

  N (girls)

33 (19)

24 (19)

15 (8)

ADOS CSS RRB

 Mean (SD)

1.12 (0.70)

3.04 (2.84)

6.13 (2.70)

F(2, 69) = 29.80, p < 0.001, η 2 = 0.463

  N (girls)

33 (19)

24 (19)

15 (8)

WASI FSIQ

 Mean (SD)

117.06 (11.61)

107.96 (12.76)

109.79 (21.36)

F(2, 70) = 3.25, p = 0.05, η 2 = 0.085

  N (girls)

35 (21)

24 (19)

14 (8)

  1. *Two LR children completed questionnaires only; an exact age at visit was not available for these children
  2. ADI Autism Diagnostic Interview—Revised, RRB Repetitive and restrictive behaviour, ADOS Autism Diagnostic Observation Schedule, CSS Calibrated severity score, SA Social affect, WASI-II Wechsler Abbreviated Scale of Intelligence—II Full-Scale IQ, n/s non-significant
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Molecular Autism

ISSN: 2040-2392