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Fig. 2 | Molecular Autism

Fig. 2

From: Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for regional phenotypes

Fig. 2

The NF1 mouse brain shows regional changes in GABA(A) α1 subunit receptor levels. Western blot analyses demonstrated that expression levels of GABA(A) receptor is up- and downregulated in hippocampal and cortical synaptosomes (a), respectively. Representative Western blot images of GABA(A)α1 receptor (50 kDa) and β-actin (42 kDa) are shown (b). Data are expressed as mean ± SEM (n = 8–14). * p < 0.05, statistical significance comparing with respectively wild-type using the Mann-Whitney’s test

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Molecular Autism

ISSN: 2040-2392