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Table 3 Comparison of CCPT performance between AS, unaffected siblings (US) of AS probands, and TD

From: ADHD-related symptoms and attention profiles in the unaffected siblings of probands with autism spectrum disorder: focus on the subtypes of autism and Asperger’s disorder

  AS (n = 77) US of AS (n = 77) TD (n = 196)   Trend test
F p Comparisona F p
Focused attention
 Omission 10.75±19.13 8.34±9.18 6.35±7.41 5.33 0.007* AS>TD 9.09 0.003**
 RT SE 10.73±7.42 10.11±6.58 8.63±5.50 7.25 0.001* AS>TD 14.60 0.000**
 Variability 23.33±25.53 19.99±17.71 16.89±16.54 4.91 0.010* AS>TD 11.91 0.001**
 Perseveration 9.26±13.78 9.31±16.57 7.02±14.31 2.00 0.142 7.50 0.007**
 Detectability 0.37±0.37 0.44±0.35 0.43±0.36 1.35 0.266 0.68 0.411
Cognitive impulsivity
 Commission 22.22±8.56 20.82±8.20 20.85±8.31 1.85 0.165 1.23 0.269
 Reaction time 396.03±89.55 399.66±83.98 381.04±67.13 4.91 0.010* AS>TD 4.25 0.040**
 Response style 0.60±0.43 0.55±0.34 0.58±1.25 0.62 0.541 2.88 0.091
Sustained attention
 Hit RT block change 0.01±0.04 0.01±0.04 0.01±0.03 2.44 0.094 4.82 0.029**
 Hit SE block change 0.09±0.12 0.06±0.13 0.04±0.09 4.59 0.013* AS>TD 6.80 0.010**
Vigilance
 Hit RT ISI change 0.09±0.05 0.08±0.05 0.08±0.04 3.15 0.049 AS>TD 5.44 0.020**
 Hit SE ISI change 0.13±0.18 0.12±0.17 0.10±0.16 1.56 0.218 2.23 0.136
  1. Abbreviations: CCPT Conners’ Continuous Performance Test; RT Reaction time; β estimate of regression coefficient; SE standard error, ISI inter-stimulus interval
  2. *False discovery rate-adjusted p < 0.05
  3. **Trend test p < 0.05
  4. aBonferroni correction p < 0.05