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Table 3 Comparison of CCPT performance between AS, unaffected siblings (US) of AS probands, and TD

From: ADHD-related symptoms and attention profiles in the unaffected siblings of probands with autism spectrum disorder: focus on the subtypes of autism and Asperger’s disorder

 

AS (n = 77)

US of AS (n = 77)

TD (n = 196)

 

Trend test

F

p

Comparisona

F

p

Focused attention

 Omission

10.75±19.13

8.34±9.18

6.35±7.41

5.33

0.007*

AS>TD

9.09

0.003**

 RT SE

10.73±7.42

10.11±6.58

8.63±5.50

7.25

0.001*

AS>TD

14.60

0.000**

 Variability

23.33±25.53

19.99±17.71

16.89±16.54

4.91

0.010*

AS>TD

11.91

0.001**

 Perseveration

9.26±13.78

9.31±16.57

7.02±14.31

2.00

0.142

7.50

0.007**

 Detectability

0.37±0.37

0.44±0.35

0.43±0.36

1.35

0.266

0.68

0.411

Cognitive impulsivity

 Commission

22.22±8.56

20.82±8.20

20.85±8.31

1.85

0.165

1.23

0.269

 Reaction time

396.03±89.55

399.66±83.98

381.04±67.13

4.91

0.010*

AS>TD

4.25

0.040**

 Response style

0.60±0.43

0.55±0.34

0.58±1.25

0.62

0.541

2.88

0.091

Sustained attention

 Hit RT block change

0.01±0.04

0.01±0.04

0.01±0.03

2.44

0.094

4.82

0.029**

 Hit SE block change

0.09±0.12

0.06±0.13

0.04±0.09

4.59

0.013*

AS>TD

6.80

0.010**

Vigilance

 Hit RT ISI change

0.09±0.05

0.08±0.05

0.08±0.04

3.15

0.049

AS>TD

5.44

0.020**

 Hit SE ISI change

0.13±0.18

0.12±0.17

0.10±0.16

1.56

0.218

2.23

0.136

  1. Abbreviations: CCPT Conners’ Continuous Performance Test; RT Reaction time; β estimate of regression coefficient; SE standard error, ISI inter-stimulus interval
  2. *False discovery rate-adjusted p < 0.05
  3. **Trend test p < 0.05
  4. aBonferroni correction p < 0.05