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Table 1 Behavioral data and statistics: Composite z-score (online) is the mean of four z-scores: spatial span backward maximum length, digit span backward maximum length, online letter n-back accuracy, and online spatial n-back accuracy. Composite z-score (offline) is the mean of three z-scores: offline letter n-back accuracy, offline spatial n-back accuracy, and BTA raw score. Composite z-score (full battery) is the mean of five z-scores: spatial span backward maximum length, digit span backward maximum length, letter n-back accuracy (mean of online and offline percentages), spatial n-back accuracy (mean of online and offline percentages), and BTA raw score. Also included are means and standard deviations for 1-back, 2-back, and 3-back for letter and spatial n-back, both online and offline

From: Balanced bifrontal transcranial direct current stimulation enhances working memory in adults with high-functioning autism: a sham-controlled crossover study

 

Sham

Left anodal

Right anodal

Repeated measures ANOVA F(2,22)

Friedman’s Test χ2

p value

WMS-III, spatial span backward, longest span (blocks)

4.8 (0.9)

6.2 (1.8)

6.0 (0.9)

 

9.24

0.01

WMS-III, digit span backward, longest span (digits)

5.3 (1.5)

5.5 (1.6)

5.4 (2.0)

0.12

 

0.891

Spatial n-back accuracy (online)

62.4% (25.0%)

68.6% (22.1%)

66.7% (23.2%)

 

3.17

0.205

 1-back

74.7% (23.1%)

80.0% (19.9%)

79.6% (21.4%)

   

 2-back

61.4% (27.9%)

68.5% (26.4%)

66.2% (25.5%)

   

 3-back

49.7% (25.8%)

55.6% (22.9%)

52.7% (25.0%)

   

Letter n-back accuracy (online)

69.6% (30.2%)

76.2% (22.5%)

76.3% (26.8%)

 

0.5

0.779

 1-back

77.3% (26.6%)

82.9% (19.9%)

84.8% (21.7%)

   

 2-back

70.4% (32.4%)

76.0% (26.0%)

76.2% (29.3%)

   

 3-back

61.1% (33.1%)

69.7% (24.2%)

68.1% (29.7%)

   

Composite z-score (online)

−0.25 (0.74)

0.15 (0.87)

0.09 (0.81)

7.68

 

0.003

Spatial n-back accuracy (offline)

63.9% (24.9%)

70.6% (20.9%)

67.7% (24.2)

0.55

 

0.758

 1-back

76.2% (21.9%)

85.1% (20.2%)

78.4% (21.7%)

   

 2-back

63.2% (29.0%)

70.5% (24.3%)

69.8% (26.8%)

   

 3-back

52.5% (26.5%)

56.3% (21.8%)

54.6% (26.0)

   

Letter n-back accuracy (offline)

72.3% (29.8%)

78.5% (22.5%)

76.5% (25.9%)

 

0.17

0.92

 1-back

80.7% (23.2%)

86.1% (20.7%)

84.3% (21.6%)

   

 2-back

71.1% (33.2%)

77.8% (22.3%)

77.8% (27.2%)

   

 3-back

65.1% (33.6%)

71.6% (26.2%)

67.4% (30.0)

   

Brief Test of Attention (offline)

6.8 (2.5)

7.4 (2.2)

7.9 (2.5)

 

7.09

0.029

Composite z-score (offline)

−0.18 (0.92)

0.09 (0.77)

0.09 (0.93)

 

7.17

0.028

Spatial n-back accuracy combined (mean of online and offline percentages)

63.2% (24.7%)

69.6% (20.7%)

67.3% (23.6%)

 

0.67

0.717

Letter n-back accuracy combined (mean of online and offline percentages)

71.0% (29.8%)

77.4% (22.1%)

76.4% (26.3%)

 

0.17

0.92

Composite z-score (full battery)

−0.25 (0.71)

0.13 (0.82)

0.11 (0.81)

12.85

 

0.0002