Skip to main content
Fig. 2 | Molecular Autism

Fig. 2

From: A brain proteomic investigation of rapamycin effects in the Tsc1 +/− mouse model

Fig. 2

Multivariate analysis of LC-MSE estimates as shown by condition plots illustrating the differences between the WT and Tsc1 +/− mice with and without rapamycin treatment. X-axis is condition and y-axis is log ratio of endogenous (L light) over reference (H heavy) peptides. Dots represent the mean of the log2 ratio for each condition, and error bars indicate the confidence intervals with 0.95 significance. The interval is not related to the model based analysis. Significant changes as measured by LC-MSE are indicated below each protein. Illustrated are examples of proteins which are affected by rapamycin treatment and which are normalized by rapamycin treatment. Corrected p values (p*) were determined by post hoc correction after Benjamini-Hochberg [91]. CR = Wt + rapamycin, CS = Wt + vehicle, TR = Tsc1 +/− + rapamycin, TS = Tsc1 +/− − rapamycin

Back to article page